Toxic Epidermal Necrolysis Managed with Immunoglobulin: Reply
نویسندگان
چکیده
منابع مشابه
Levofloxacin-induced toxic epidermal necrolysis treated with intravenous immunoglobulin.
Dear Editor, Toxic Epidermal Necrolysis (TEN) is a rare, fulminating rash with a mortality rate of 35%.1 It is predominantly medication-induced; allopurinol, ampicillins, anticonvulsants and non-steroidal anti-inflammatory drugs are commonly implicated. Fluoroquinolones are widely used, have a broad coverage and have a low incidence of serious adverse effects. Levofloxacin, a L-racemic isomer o...
متن کاملCephalosporin-Induced Toxic Epidermal Necrolysis Treated with Intravenous Immunoglobulin
Toxic epidermal necrolysis (TEN) is a life-threatening cutaneous reaction to various medications, including antipsychotics and antibiotics. While cephalosporin-induced TEN is very rare, we present a case of cefepime-induced TEN. There are several commonly used therapies for TEN, including immunosuppressive agents and intravenous immunoglobulin (IVIG), but their true efficacy has not been proven...
متن کاملTreatment of toxic epidermal necrolysis with intravenous immunoglobulin.
Toxic epidermal necrolysis is a severe adverse drug reaction that produces extensive mucocutaneous damage, with full-thickness epidermal detachment, and has many clinical similarities to severe burn injuries. The treatment is mainly supportive and aimed at preventing complications while the disease takes its natural course, and the skin reepithelializes. Much interest exists in the development ...
متن کامل[Toxic epidermal necrolysis].
Toxic epidermal necrolysis is a potentially fatal dermatological disease. Large bullae covering extensive areas of the body cause continuous exfoliation of skin, which requires immediate medical attention. Intraoral manifestations may precede cutaneous lesions. Two cases with different treatment protocols are presented.
متن کاملToxic Epidermal Necrolysis
Figure 1. Generalized epidermolysis on anterior and posterior torso with crusty erosions on oral mucosa. DESCRIPTION A 33-year-old woman presents with diffuse rash 3 weeks after completing a course of Bactrim for a urinary tract infection. Erythematous maculopapular rash is evident on the trunk and extremities with painful, epidermal sloughing on the back leaving a moist, denuded dermis. Note t...
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ژورنال
عنوان ژورنال: Medical Journal Armed Forces India
سال: 2009
ISSN: 0377-1237
DOI: 10.1016/s0377-1237(09)80082-8